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In Figure A, depolarization, demonstrated by red positive charges inside and red negative charges outside, is traveling from left to right. The first half of the fiber has already depolarized while the remaining half is still polarized.
Therefore, the left electrode on the outside of the fiber is in an area of negativity, and the right electrode is in an area of positivity, which causes the meter to record positively.
To the right of the muscle fiber is shown a record of changes in potential between the two electrodes, as recorded by a highspeed recording meter. Note that when depolarization has reached the halfway mark in Figure A, the recording on the right has risen to a maximum positive value.
In Figure B, depolarization has extended over the entire muscle fiber, and the recording to the right has returned to the zero baselines because both electrodes are now in areas of equal negativity. The completed wave is a depolarization wave because it results from the spread of depolarization along the muscle fiber membrane.
Figure C shows halfway repolarization of the same muscle fiber, with positivity returning to the outside of the fiber. At this point, the left electrode is in an area of positivity, and the right electrode is in an area of negativity.
This polarity is opposite to the polarity in Figure 2A. Consequently, the recording, as shown to the right, becomes negative. In Figure D, the muscle fiber has completely repolarized, and both electrodes are now in areas of positivity so that no potential difference is recorded between them.
Thus, in the recording on the right, the potential returns once more to zero. This completed negative wave is a repolarization wave because it results from the spread of repolarization along the muscle fiber membrane. Find other books of Guyton and Hall Books here. Your email address will not be published. We have currently put here 3rd edition of Guyton and Hall Physiology Review pdf for download.
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